NR. 4/2004



Zmiany przepływu krwi w tętnicy ¶rodkowej siatkówki u chorych z such± i wysiękow± postaci± starczego zwyrodnienia plamki, oceniane metod± USG Color Doppler

Changes in the central retinal artery blood flow in patients with exudative and non-exudative age-related macular degeneration (AMD) evaluated with US Color Doppler method use


Małgorzata Wojnar1, Zofia Mariak1, Andrzej Ustymowicz2, Jolanta Andrzejewska-Buczko1


1Klinika Okulistyki Akademii Medycznej w Białymstoku
Kierownik: dr hab. med. Zofia Mariak
2Zakład Radiologii Akademii Medycznej w Białymstoku
Kierownik: prof. dr hab. med. Jerzy Walecki

Summary: Aim of the study: To evaluate the changes in the blood flow in the central retinal artery in patients with exudative and non-exudative age-related macular degeneration (AMD).
Material and methods: 51 patients, aged 64-91, with both forms of age-related macular degeneration (33 women and 18 men) were examined. Patients were divided into two groups: I – 7 persons (9 eyes) with exudative AMD and group II- 44 persons (64 eyes) with non-exudative AMD. In all cases the Power Color Doppler flowmetry was conducted using 9 MHz Siemens Elegra. Peak systolic (PS), End diastolic (ED) and resistance index were measured. The obtained results were compared to the control group of the same age and were statistically analysed with U Mann-Withney test.
Results: Statistically significant differences in peak systolic and end diastolic velocities were obtained in central retinal artery in both AMD groups. Resistance index was also statistically higher in comparison to the control group.
Conclusions: 1. There is a distinct, statistically confirmed correlation between degree of changes of the retina and the decrease of the retinal blood flow obtained in the central retinal artery. 2. The perturbations in the blood flow may be crucial factor in the pathogenesis of exudative and non-exudative age-related macular degeneration.
 
Key words: Age-related Macular Degeneration, Color Doppler, central retinal artery.



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