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NR. 4/2004
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Zastosowanie badania
autofluorescencji dna oka w systemie konfokalnego skaningu
laserowego w obrazowaniu chorób siatkówki związanych z wiekiem
Use of the eye fundus autofluorescence examination in a system
of laser confocal scanning ophthalmoscope in age-related retinal
disease imaging
Joanna Dolar-Szczasny1,
Jerzy Mackiewicz1, Frank G. Holz2,
Zbigniew Zagórski1
1Katedra i I Klinika Okulistyki Akademii Medycznej w
Lublinie
Kierownik: prof. dr hab. med. Zbigniew Zagórski
2Klinika Okulistyczna Uniwersytetu w Bonn
Kierownik: prof. dr hab. med. Frank G. Holz |
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| Summary: |
Our article introduces an
issue of fundus autofluorescence which originates at the
level of the retinal pigment epithelial (RPE) cells and
that is derived from lipofuscin accumulation.
Autofluorescence imaging in confocal system is a new
method of retinal pigment epithelium layer visualization
and a useful tool in the diagnosis of different
age-related retinal diseases: AMD, macular hole and
reticular drusen.
This method gives a possibility for better understanding
of pathogenetic mechanisms in various retinal diseases
and is useful for monitoring the course of diseases. As
a non-invasive technique in some cases it can replace or
complement other diagnostic tools. |
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| Key words: |
autofluorescence, confocal
scanning laser ophthalmoscope, lipofuscin, age-related
macular degeneration (AMD), idiopathic macular hole,
reticular drusen. |
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