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NR. 4/2004
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Ocena stężenia
interferonu-gamma we łzach w przebiegu zespołu suchego oka
The level of interferon-gamma in tear fluid in dry eye syndrome
Małgorzata Mrugacz, Alina
Bakunowicz-Łazarczyk, Nella Żywalewska
Klinika Okulistyki Dziecięcej Akademii Medycznej w Białymstoku
Kierownik: prof. dr hab. med. Alina Bakunowicz-Łazarczyk |
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| Summary: |
Purpose: To
evaluate IFN- g concentration in tear fluid in non-SS
dry eye.
Material and methods: Tear samples were collected
from 22 non-SS dry eye patients aged 33-55, and 15
controls aged 30-50. Cytokine levels were determined by
ELISA.
Results: The concentration of IFN-g in tear fluid
in non-SS dry eye patients was 7.44±2.75 pg/ml, and
4.72±1.16 pg/ml in controls.
Conclusions: IFN-g concentration in tear fluid is
significantly higher in non-SS dry eye patients than
controls. These results suggest that INF-g may play a
role in the immune-based inflammatory pathogenesis of
non-SS dry eye. |
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| Key words: |
dry eye syndrome,
interferon-gamma, cytokines. |
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