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NR. 1/2005
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Asymetria parametrów
stereometrycznych tarczy nerwu wzrokowego i warstwy włókien
nerwowych w diagnostyce jaskry pierwotnej otwartego kąta
Asymmetry of Stereometric Parameters of the Optic Disc and
Retinal Nerve Fiber Layer in Primary Open Angle Glaucoma
Diagnosis
Piotr Wasilczuk, Renata Zalewska,
Zofia Mariak
Klinika Okulistyki Akademii Medycznej w Białymstoku
Kierownik: dr hab. med. Zofia Mariak |
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| Summary: |
Aim of the study was to
compare stereometric parameters of the optic disc and
retinal nerve fiber layer (RNFL) in both eyes of healthy
volunteers and in patients with primary open angle
glaucoma (POAG).
Material and methods: 50 healthy volunteers (control
group) were qualified for further study. There were 30
females and 20 males, aged 46-81 years (mean 59.7 ±
9.57) and 50 patients with POAG, 38 females and 12 males,
aged 45-72 years (mean 59.26 ± 7.42). In all examined
patients we evaluated stereometric parameters of the
optic disc and RNFL using HRT II device. Results were
statistically analyzed with Mann-Whitney U test and
logistic regression pattern.
Results: Comparative analysis of patients with
POAG and control group showed, that in all stereometric
parameters of the optic disc and RNFL, both groups were
statistically different. According to the logistic
regression analysis, the most differentiating parameters
between both groups were C/D and LC/D.
Comparative analysis of the stereometric parameters in
both eyes in control group showed, that the highest
statistic differentiating impact was achieved with
following parameters: RV, RNFL RNFLCSA and HVC. Logistic
regression analysis pointed on RNFL, as the best
differentiating parameter.
Based on comparative analysis of stereometric parameters
in POAG group we found, that the most important
difference between both eyes was statistically
significant in: RV, C/D, LC/D, CA, RA and RNFLCSA.
Logistic regression analysis found LC/D to be the most
important differentiating parameter.
Conclusions:
1. Confocal scanning laser tomography (HRT II)
examination allows to exactly analyze stereoscopic
parameters of the optic disc, their acquisition and
comparison.
2. Asymmetry of RNFL parameter may suggest the presence
of glaucomatous damage in prepe-
rimetric period.
3. Asymmetry of LC/D parameter is characteristic for
advanced (perimetric) glaucoma. |
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| Key words: |
primary open angle
glaucoma, confocal scanning laser tomography (HRT II),
optic disc topography. |
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