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NR. 4/2006
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Zastosowanie
fotochemoterapii w leczeniu guzów wewnątrzgałkowych
Photochemotherapy in Treatment of Intraocular Tumors
Agnieszka Kubicka-Trząska, Bożena
Romanowska-Dixon
Klinika Okulistyki i Onkologii Okulistycznej Katedry Okulistyki
Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie
Kierownik: dr hab. n. med. Bożena Romanowska-Dixon |
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| Summary: |
Phototherapy has been
known since antiquity, but it has become center of
interest of experimental and clinical research at the
beginning of the 20th century. The turning point in
phototherapy were studies on porphyria. Bruce and Tse
published their pioneer works about phototherapy with
hematoporphyrin in ocular tumors in 1984. At present in
ocular oncology photodynamic therapy with verteporfin
and indocyanine green mediated phototherapy are used in
management of selected cases of intraocular tumors. Both
methods are based on selective occlusion of tumors
intrinsic vasculature as a result of photosensitizers
activation (verteporfin and indocyanine green dye) with
low energy laser. We are going to present the overview
of the literature and our own results of therapy of some
cases of choroidal melanomas and choroidal haemangiomas
with both of these methods. |
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| Key words: |
photochemotherapy,
photodynamic therapy, indocyanine green mediated
photothrombosis, intraocular tumors. |
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