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NR. 3(I)/2007
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Układ naczyniowy
tylnego odcinka błony naczyniowej u ludzi zdrowych i chorych
Vascular System of the Posterior Part of the Choroid in Healthy
and Sick Individuals
Marta Misiuk-Hojło1,
Dorota Szumny2
1Katedra i Klinika Okulistyki Akademii Medycznej we
Wrocławiu
Kierownik: dr hab. n. med. Marta Misiuk-Hojło
2Katedra i Zakład Farmakologii Akademii Medycznej we
Wrocławiu
Kierownik: prof. dr hab. Adam Szeląg |
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| Summary: |
Choriocapillaris is lying
in unique place- just behind Bruch’s membrane and
retinal pigment epithelial cells. In health and disease
they are engaged not only in choroidal but also retinal
processes. Researchers found out a method to mark an
endogeneous alkaline phosphatase in choroideal
endothelium cells, that helps to demonstrate choroidal
vascular system with the surrounding tissues. This
method became important to evaluate choroid vascular
changes in diabetes and age-related macular degeneration.
In these diseases vascular system failure leads to
tissue hypoxia and in consequence to damage and
proliferation of vessels. Damaged or abnormal
functioning choroid vessels do not have endogenous
alkaline phosphatase activity but in choroidal
neovascularization this activity is higher. |
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| Key words: |
choroidea,
choriocapillaris, age-related macular degeneration,
diabetes. |
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