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NR. 3(I)/2007
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Częstość
występowania druz u chorych ze starczym zwyrodnieniem plamki –
wyniki własne
Insidence of Drusen in Age-Related Macular Degeneration – Own
Results
Barbara Terelak-Borys, Irmina
Jankowska-Lech, Iwona Liberek
Oddział Okulistyki Centrum Medycznego Kształcenia Podyplomowego
Samodzielnego Publicznego Szpitala Klinicznego im. prof.
Orłowskiego w Warszawie
P.o. kierownik: dr n. med. Iwona Liberek |
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| Summary: |
Purpose: Retinal
drusen are now considered one of the most important
local risk factor for the development of age-related
macular degeneration (AMD). The aim of the study was to
analyse coexistance of drusen, regarded as related to
AMD development, with two forms of AMD: exudative (classic
and occult choroidal neovascular membranes and
subretinal scars) and advanced atrophic (geographic
atrophy).
Material and methods: Fundus angiographic
examinations of 65 patients with AMD: 54 patients aged
55-85 years with exudative AMD and 11 patients aged
67-83 years with atrophic AMD were analysed
retrospectively. Fundus angiography was performed with
confocal scanning laser angiograph HRA (Heidelberg
Retina Angiograph, Heidelberg Engineering, Germany)
which offers possibility of simultaneous fluorescein
angiography (FA) and indocyanine green angiography (ICGA)
examination.
Results: Significantly higher insidence of drusen,
regarded as related to AMD development, was detected in
patients with age-related macular degeneration (60% in
the exudative form and 81,8% in the atrophic form) in
comparison with the control group (14.3%) (p=0.0011,
p=0.0045 respectively).
Conclusions: Results of our study confirm
relationship of drusen with the pathogenesis of AMD.
They also suggest that drusen may be more closely
related to the development of AMD atrophic form. |
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| Key words: |
drusen, age-related
macular degeneration, fluorescein angiography,
indocyanine green angiography. |
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