NR 3-4/2003
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Wpływ miejscowo podawanych jodków na
wydalanie jodu i funkcję tarczycy
Influence of topically apllied iodides on urinary
iodine excretion and thyroid function
Andrzej Stankiewicz, Maksymilian Siekierzyński1, Joanna
Wierzbowska
Z Kliniki Okulistycznej Wojskowego Instytutu Medycznego w Warszawie
Kierownik: prof. dr hab. n. med. Andrzej Stankiewicz
1Z Kliniki Endokrynologii Wojskowego Instytutu Medycznego w Warszawie
Kierownik: prof. dr hab. n. med. Maksymilian Siekierzyński |
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| Summary: |
Purpose: The present study was undertaken,
to evaluate whether ophthalmic drug, containing iodine applied to conjunctivall sac might
result in a significant increase of urine iodine excretion and thus might be undirectly
associated with the risk of iodine-induced hyperthyroidism. The aim of the study was to
examine the occurance of biochemically relevant changes in urine iodine excretion and in
thyroid function after topical administration of ophthalmic drug containing iodine.
Material and methods: In the study twenty-two patients without a history
of thyroid disease were examined. The Vitreolent (Ciba Vision) was applied topically to
conjunctival sac four times a day for one month. The urinary iodine excretion, using
"Rapid Urinary Iodine Test" (Merck KgaA) and parameters of thyroid function
(TSH, FT3 , FT4) were measured before starting and after therapy.
Results: The data showed, that was a significant increase in urinary
iodine excretion at the end of therapy; as far as thyroid function was concerned, neither
changes in level of TSH nor thyroid hormones were observed. |
| Słowa kluczowe: |
leki okulistyczne zawierające jod, wydalanie jodków z
moczem, funkcja tarczycy. |
| Key words: |
ophthalmic drugs containing iodine, urinary iodine
excretion, thyroid function. |
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