NR 3-4/2003
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Trombofilia jako czynnik ryzyka zakrzepicy żyły
¶rodkowej siatkówki
Thrombophilia as a risk factor of central retinal vein
occlusion
Anetta Undas1, Agnieszka Kubicka-Trz±ska2
1Z II Katedry Chorób Wewnętrznych Collegium Medicum Uniwersytetu Jagiellońskiego
w Krakowie
Kierownik: prof. dr hab. n. med. Andrzej Szczeklik
2Z Kliniki Okulistyki Collegium Medicum Uniwersytetu Jagiellońskiego w
Krakowie
Kierownik: prof. dr hab. n. med. Maria Starzycka |
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| Summary: |
Central retinal vein occlusion is associated with systemic
conditions, such as arterial hypertension, diabetes, hypercholesterolemia, but also with
certain hypercoagulability states (thrombophilia). Growing evidence indicates, that the
presence of antiphospholipid antibodies and elevated plasma homocysteine levels predispose
to central retinal vein occlusion. In younger patients, factor V Leiden (Arg506Gln) could
increase the risk of this disease. Other probable causes of thrombophilia related to
retinal vein occlusion include increased levels of plasminogen activator inhibitor 1 and
lipoprotein (a), which impair fibrinolysis. |
| Słowa kluczowe: |
zakrzepica żyły ¶rodkowej siatkówki, trombofilia,
przeciwciała antyfosfolipidowe, homocysteina. |
| Key words: |
central retinal vein occlusion, thrombophilia,
antiphospholipid antibodies, homocysteine. |
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