NR 6/2003

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Zastosowanie zieleni indocyjaninowej w
leczeniu fotodynamicznym neowaskularyzacji podsiatkówkowej w przebiegu zwyrodnienia
plamki związanego z wiekiem - doniesienie wstępne
Photodynamic therapy with indocyanine green for
choroidal neovascularization caused by age-related macular degeneration
- a preliminary report
Agnieszka Kubicka-Trząska, Maria Starzycka
Z Katedry i Kliniki Okulistyki Collegium Medicum Uniwersytetu Jagiellońskiego
Kierownik: prof. dr hab. n. med. Maria Starzycka |
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| Summary: |
Purpose: To evaluate the usefulness of
indocyanine green in the photodynamic therapy (iPDT) of choroidal neovascularization (CNV)
in age-related macular degeneration (AMD).
Material and methods: Twelve patients with choroidal neovascularization
secondary to AMD were treated with iPDT. Therapy was performed with 810 nm diode laser
after intravenous injection of 25 mg solution of indocyanine green. Within 3 months
follow-up two visits were performed with ICGA images evaluation, at each control.
Results: After therapy complete regression of the CNV was demonstrated by
ICGA in 3 cases, partial regression was found in 5 patients, 3 revealed no changes and in
one case the progression of the CNV was noted in spite of the treatment. Six patients
presented increase in visual acuity, in 5 no changes were observed, and in one case a
2-line decrease in VA was detected by 3 months of follow-up.
Conclusions: Our preliminary study suggests that ICG mediated PDT can be
a new and promising way, to treat neovascular AMD. |
| Słowa kluczowe: |
leczenie fotodynamiczne, zieleń indocyjaninowa,
neowaskularyzacja podsiatkówkowa, zwyrodnienie plamki związane z wiekiem. |
| Key words: |
photodynamic therapy, indocyanine green, choroidal
neovascularization, age-related macular degeneration. |
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