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NR 1-2/2004
SUPLEMENT
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Poziom przeciwciał
skierowanych przeciwko beta-2 glikoproteinie I w surowicy i
cieczy wodnistej pacjentów z jaskrą i ich wpływ na występowanie
zmian w perymetrii statycznej
The antibodies anty beta-2
glikoprotein I level in serum and aqueous humor in patients with
glaucoma and their influence on the static perimetry
Małgorzata Latalska1, Marek
Gerkowicz1, Ewa Kosior-Jarecka2,
Maria Kozioł-Montewka2, Małgorzata Pietraś-Trzpiel1
1Z II Kliniki Okulistyki Akademii Medycznej im. prof.
Feliksa Skubiszewskiego w Lublinie
Kierownik: dr hab. n. med. Marek Gerkowicz
2Z Katedry i Zakładu Mikrobiologii Lekarskiej
Akademii Medycznej im. prof. Feliksa Skubiszewskiego w Lublinie
Kierownik: prof. dr hab. n. med. Maria Kozioł-Montewka |
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| Summary: |
Purpose: The
evaluation of the relationships between the antibodies
anty beta-2 glikoprotein I in serum and aqueous humor of
the glaucoma patients to the visual field defects.
Material and methods: 48 persons (38 women and 17
men), aged 30-86 (mean age 70), suffering from glaucoma
was examined. There were 19 with POAG, 18 with PACG and
11 with PEXG. All patients have undergone
trabeculectomia. In plasma and anterior chamber fluid
the level of antibodies to beta-2 glicoprotein I classes
IgA and IgG were measured using ELISA method (commercial
kits produced by Euroimmun), according to producer's
instruction. The visual field defects were examined with
Humphrey static perimetry. Statistical analysis was
performed using Spearman test.
Results: There were no significant correlations
between antibodies anty beta-2 glikoprotein I, static
perimetry, age and duration of the disease.
Conclusions: There have not been stated any
relationships between the static perimetry to
antiphospholipid antibodies level in serum and aqueous
humor in patients with glaucoma. It is the preliminary
communication. |
| Słowa kluczowe: |
jaskra, przeciwciała
przeciwko beta-2 glikoproteinie I, surowica, ciecz
wodnista, perymetria. |
| Key words: |
glaucoma, antibodies to
beta-2 glikoprotein I, serum, aqueous humor, perimetry. |
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