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NR 1-2/2004
SUPLEMENT
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Zastosowanie
mitomycyny C w operacyjnym leczeniu jaskry – ocena skuteczności
i działań ubocznych preparatu stosowanego śródoperacyjnie,
miejscowo
Intraoperative use of
mitomycin C in glaucoma filtering surgery – indications, results
and complications
Anna Zaleska-Żmijewska, Jerzy Szaflik
Katedra i Klinika Okulistyki II Wydziału Lekarskiego Akademii
Medycznej w Warszawie
Samodzielny Publiczny Kliniczny Szpital Okulistyczny
Kierownik: prof. dr hab. n. med. Jerzy Szaflik |
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| Summary: |
Purpose: The
influence of MMC on the cornea, especially on the
corneal endothelium and thickness, were checked.
Material and methods: In one-year-follow up
patients after trabeculectomies with or without topical
use of mitomycin C were controlled for early and late
complications, and levels of intraocular pressure. The
progression of glaucomatous neuropathy was obtained by
comparing the cup to disc ratio and some parameters of
static visual field testing (MD, PSD) progressions,
after one year observations.
Results: intraocular pressures were stable and at
lower levels in the group of patients after primary
trabeculectomies (group C) than in the control group (group
A). We obtained good, statistically significant decrease
in IOP in all groups during one year follow-up.
Conclusions: We didn't find any toxic effects of
MMC, given on a sponge during trabeculectomy, on the
morphology and physiology of the corneal endothelium and
the central corneal thickness. We also didn't note any
differences between groups in the progression of
glaucomatous optic nerve damaged and cataract after 1
year follow up. |
| Słowa kluczowe: |
jaskra, trabekulektomia,
antymetabolity, mitomycyna C, śródbłonek rogówki. |
| Key words: |
glaucoma, trabeculectomy,
antimetabolites, mitomycin C, corneal endothelium cells. |
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