NR 1-2/2004
SUPLEMENT


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Skuteczność latanoprostu w jaskrze wieku dziecięcego

The effectiveness of latanoprost for the treatment of pediatric glaucoma

Beata Urban, Alina Bakunowicz-Łazarczyk, Małgorzata Mrugacz, Monika Oziębło-Kupczyk

Z Kliniki Okulistyki Dziecięcej Akademii Medycznej w Białymstoku
Kierownik: prof. dr hab. n. med. Alina Bakunowicz-Łazarczyk

Summary: Latanoprost is a prostaglandin F2a analog that reduces intraocular pressure by 20-40% in adults with open-angle glaucoma. The efficacy and safety of this drug in children has not been widely reported. In our study we evaluated the effect of latanoprost in 14 children aged 12-18 years (mean 15 years): 10 patients with glaucoma juvenile (I group); 2 patients with secondary glaucoma because of uveitis recidivans and 2 patients with aniridia and albinismus (II group). In the I group the average IOP decrement was 9 mmHg or 36,5% (range 29-44%). In the II group the average IOP decrement was 6,5 mmHg or 23,5% (range 11-33%). In one child with aniridia after one year of treatment IOL rose again to 26 mmHg and antiglaucomatous surgery was necessary. Ocular side effects in children of latanoprost are mild.
Słowa kluczowe:  latanoprost, jaskra dziecięca.
Key words: latanoprost, children, glaucoma.



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