NR 3/2004
SUPLEMENT


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Wpływ opsonin na fagocytozę erytrocytów znajdujących się w ciele szklistym – badania laboratoryjne (część A)

The effect of opsonins on erythrocytes phagocytosis in the vitreous-laboratory research (part A)

Krystyna Raczyńska, Barbara Iwaszkiewicz-Bilikiewicz

Z Katedry i Kliniki Chorób Oczu Akademii Medycznej w Gdańsku
Kierownik: prof. dr hab. n. med. Barbara Iwaszkiewicz-Bilikiewicz

Summary: Purpose: We performed experimental investigations in vitro into the opsonization of Rh-positive erythrocytes by IgG anti-RhD antibodies and phagocytosis of erythrocytes in the vitreous body.
Material and methods: The vitreous has been taken from the corpses of young people. Anti-RhD antibodies came from preparations 'Gamma anti-D 150'. 1% Erytrocyte suspension of ccDee phenotype has been applied. Phagocytosis assay was performed in the medium of the vitreous and in Hank's solution.
Results: Phagocytosis assay performed in the vitreous and in Hank's solution did not display statistically significant differences.
Conclusions: The investigations in vitro presented here, proved that immunological reactions are really occurring in the vitreous body. They provide a base for the explanation of activity mechanism of anti-RhD antibodies injected intraoculary in cases of hemorrhages into vitreous body.
Słowa kluczowe:  IgG anty – RhD, adherencja, fagocytoza, ciało szkliste – krwotoki.
Key words: IgG anti – RhD, adherence, phagocytosis, vitreous hemorrhage.



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