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NR 3/2004
SUPLEMENT
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Lipoproteiny osocza
chorych z niewysiękową postacią AMD leczonych miejscowo
betablokerami
Serum lipid profile in
non-exudative AMD patients treated with locally administrated
beta-blockers
Andrzej Gębka, Barbara
Iwaszkiewicz-Bilikiewicz, Krystyna Raczyńska, Magdalena Homziuk,
Cezary Ciechanowski
Z Katedry i Kliniki Chorób Oczu Akademii Medycznej w Gdańsku
Kierownik: prof. dr hab. n. med. Barbara
Iwaszkiewicz-Bilikiewicz |
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| Summary: |
Reduced perfusion in the
choroidal vessels has been proposed as the vascular
pathogenesis for AMD. As no specific therapy is
currently available, the authors decided to evaluate the
possible benefits of topically administrated betaxolol
in non-exudative AMD patients. 114 randomly selected
patients with NE AMD was divided into 2 groups: group I
(64 patients) and group II (50 patients). The subjects
in group I have been treated with topical 0,5% betaxolol,
while in the group II with artificial tears twice daily
for one year. None of the patients had received prior
topical or systemic treatment lowering IOP. The subjects
in both groups had follow-up for 1 year, during which
lipoproteins' profile sampling was performed twice at
baseline and after 52 weeks. Both, baseline and outcome
measures included: complete ophthalmologic examination.
The changes in serum lipoproteins levels varied, but the
statistical analyze did not show the significant
differences. |
| Słowa kluczowe: |
AMD, lipoproteiny osocza,
b-blokery. |
| Key words: |
AMD, serum lipoproteins,
betablockers. |
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