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NR 3/2004
SUPLEMENT
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Poziom karnityny w
soczewce ludzkiej a stopień zaawansowania zaćmy
Carnitine level in human
lens and density of cataract
Maciej Gawęcki1, Krystyna
Raczyńska2, Magdalena Homziuk2, Barbara
Iwaszkiewicz-Bilikiewicz2
1Z Oddziału Okulistycznego Wojewódzkiego Szpitala
Zespolonego w Elblągu
Ordynator: lek. med. Janusz Adamski
2Z Katedry i Kliniki Chorób Oczu Akademii Medycznej w
Gdańsku
Kierownik: prof. dr hab. n. med. Barbara
Iwaszkiewicz-Bilikiewicz |
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| Summary: |
Purpose: To
evaluate whether the level of carnitine in human lens is
affected by development of cataract.
Material and methods: The study covers 52 cases
of cataract lenses extracted by ECCE. The nucleus of
each lens was analyzed according to the level of total
and free carnitine.
The amount of cataract was determined by the microscopic
and ophthalmoscopic examination. Cataracts were divided
into 3 groups depending on the advanced degree of
cataract.
Results and conclusions: It was possible to find
statistically significant difference in mean carnitine
level of total and free carnitine between lenses with
mature cataract and lenses with partial cataract. This
level was lower approximately by 30% in the lenses with
dense opacification. This could be another proof for
protective role of carnitine in development of human
cataract and could trigger more research on the subject
of its supplementation in patients in older age. |
| Słowa kluczowe: |
karnityna, zaćma. |
| Key words: |
carnitine, cataract. |
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