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NR 4-5/2004
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Some clinical
implications of the collaborative normal tension glaucoma study
Badania wieloośrodkowe
jaskry z niskim ciśnieniem – implikacje kliniczne
Stephen M. Drance, OC., MD
Department of Ophthalmology, University of BC, Vancouver, Canada
Head: Stephen M. Drance, OC., MD |
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| Summary: |
This is to present the
results of randomized multicenter normal tension
glaucoma study. The primary aim of the study was to
establish whether a 30% or greater pressure reduction
altered the course of NTG compared to untreated controls.
Our study confirms that in glaucoma patients even with
normal intraocular pressures the pressure is involved in
its pathogenesis and that pressure reduction favourably
affects its course in a significant proportion of cases.
Moreover, it identifies a great variability of the
untreated disease. Over 7 years nearly half appeared to
show no progression, the other half showed progression
of their damaged area but this was slow and often did
not result in a change of their MD index. There was a
small group, who showed rapidly advancing disease, which
was likely lead to visual handicap. Moreover, it was
then attempted to study risk factors, other than
intraocular pressure. Gender, ethnic background,
migraine and the presence of disc hemorrhage adversely
influence the course of the disease and may therefore
account for some of the variability in the course of the
disease. |
| Słowa kluczowe: |
normal tension glaucoma,
randomized multicenter study. |
| Key words: |
jaskra normalnego
ciśnienia, wieloośrodkowe badania randomizowane. |
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