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NR 4-5/2004
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Allogeniczny
przeszczep r±bkowo-rogówkowy i wielowarstwowy przeszczep błony
owodniowej w rekonstrukcji powierzchni oka po ciężkich
oparzeniach chemicznych
Keratolimbal allografts and
multilayer amniotic membrane transplantation in the treatment of
ocular surface disease due to chemical burns
Piotr Jurowski, Roman Go¶
Z Kliniki Okulistyki i Rehabilitacji Wzrokowej Uniwersyteckiego
Szpitala Klinicznego nr 2 im. WAM Uniwersytetu Medycznego w
Łodzi
Kierownik: prof. dr hab. n. med. Roman Go¶ |
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| Summary: |
Purpose: To analyze
the functional effect and to present the technique of
keratolimbal allograft and multilayer amniotic membrane
transplantation for the treatment of ocular surface
disease after heavy chemical burn.
Materaial and methods: Treatment comprised 3 eyes
of 2 patients suffering form ocular surface deficiency
after chemical (acid) burn. Surgeries were provided
under local anesthesia. After circumferential peritomy
and removal of fibrovascular layer, stem cells in the
fashion of keratolimball crescent allograft, following
by multilayer amniotic membrane transplantation were
performed.
Results: 3 months after surgery the corneal
surface was covered with fully differentiated epithelium
in all patients. In two of three patients, improvement
of the visual acuity was also observed. However, in one
eye despite good epithelium maintenance the stroma was
still not transparent.
Conclusion: Keratolimbal allograft with
multilayer amniotic transplantation is interesting
method of ocular surface reconstruction. Combined
procedure with use of two different tissues seems to be
relevant among patients with bilateral ocular surface
dysfunction with complete destruction of stem cells
after chemical burn. |
| Słowa kluczowe: |
oparzenia chemiczne oka
choroby powierzchni oka, allogeniczny przeszczep komórek
pnia, przeszczep r±bkowo- rogówkowy, błona owodniowa. |
| Key words: |
chemical burns, ocular
surface diseases, limbal stem cells allograft,
keratolimbal allograft, amniotic membrane. |
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