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NR 10-12/2005
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Wzrokowe potencjały
wywołane u dzieci z podwyższonym poziomem ołowiu we krwi
Visual evoked potentials in
children with high blood lead level
Dorota Pojda-Wilczek1, Ewa
Herba1, Barbara Schneiberg2
1Z Katedry i Oddziału Klinicznego Okulistyki ¦l±skiej
Akademii Medycznej
Szpital Specjalistyczny nr 1 w Bytomiu
Kierownik: prof. dr hab. n. med. Stefan M. Pojda
2Z Katedry i Kliniki Pediatrii, Nefrologii i
Endokrynologii Dziecięcej ¦l±skiej Akademii Medycznej w Zabrzu
Kierownik: prof. dr hab. n. med. Antoni Dyduch |
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| Summary: |
Purpose: The aim of
this study is to find the relationship between lead
level in blood (Pb-B) and visual evoked potentials (VEP)
in children, environmentally exposed to lead.
Material and methods: 32 children (64 eyes) with
no clinical signs of lead poisoning were examined.
Corrected visual acuity was 5/5 in all eyes. Age of the
children was 2 – 15.5 years (mean 8), Pb-B ranged from
150 to 486 (mean 262) µg/l. For pattern VEP LKC
equipment, UTAS E-2000 program and stimulations of 13’,
26’, 52’, 105’ were used. P100 amplitude and latency
were calculated.
Results: P100 latency was significantly delayed
in children at the age of seven, with Pb-B above 150
µg/l. The latencies were more delayed in children with
higher than in lower Pb-B, but the relation was not
linear. P100 amplitudes did not differ significantly
from the control group. In some children VEP had
abnormal morphology, double P100 peak or P100 without
sharp, but extended peak.
Conclusion: Delayed P100 PVEP latency occurred in
children with blood lead level higher than150 µg/l,
after at least 7 years of environmental exposure.
Changes in VEP are similar to those which are caused by
demyelinization and are found in multiple sclerosis. |
| Słowa kluczowe: |
potencjały wywołane
wzrokowe, zatrucie ołowiem, dzieci. |
| Key words: |
visual evoked potentials,
lead poisoning, children. |
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