NR 10-12/2005

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Wzrokowe potencjały wywołane u dzieci leczonych wersenianem sodowo-wapniowym z powodu podwyższonego poziomu ołowiu we krwi – badanie prospektywne

Visual evoked potentials in children cured with sodium-calcium versenate because of high blood lead level – the prospective study

Dorota Pojda-Wilczek1, Ewa Herba1, Barbara Schneiberg2

1Z Katedry i Oddziału Klinicznego Okulistyki ¦l±skiej Akademii Medycznej
Szpital Specjalistyczny nr 1 w Bytomiu
Kierownik: prof. dr hab. n. med. Stefan M. Pojda
2Z Katedry i Kliniki Pediatrii, Nefrologii i Endokrynologii Dziecięcej ¦l±skiej Akademii Medycznej w Zabrzu
Kierownik: prof. dr hab. n. med. Antoni Dyduch

Summary: Purpose: To find out if blood lead level (Pb-B) changes have influence on visual evoked potentials.
Material and methods: 18 children (36 eyes) treated with CaNa2EDTA because of chronic environmental lead poisoning were examined two times: first at age 2 – 15.5 (mean 8) years and second 4 years later. For pattern VEP LKC equipment, UTAS E-2000 program and stimulations of 13’, 26’, 52’, 105' were used. P100 amplitude and latency were calculated.
Results: Pb-B was decreased from 150-486 (mean 262) µg/l to 42-248 (mean 103) µg/l. After 4 years, P100 latency was significantly delayed in children with Pb-B above 100 µg/l at second examination. In children with Pb-B below 100 µg/l no significant differences between two consecutive examinations were observed. There were no significant differences in P100 amplitude.
Conclusions: Delayed P100 latency of PVEP in children is permanent but non-progressive if Pb-B is lower than 100 µg/l.
Słowa kluczowe:  potencjały wywołane wzrokowe, zatrucie ołowiem, dzieci.
Key words: visual evoked potentials, lead poisoning, children.



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