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NR 1-3/2005
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Analiza powikłań
brachyterapii 125I w czerniakach naczyniówki
The analysis of I125
brachytherapy complications
in cases of uveal melanoma
Arkadiusz Pogrzebielski, Maria Starzycka,
Bożena Romanowska-Dixon, Barbara Jakubowska, Urszula Szpakowicz
Z Katedry i Kliniki Okulistyki Collegium Medicum Uniwersytetu
Jagiellońskiego w Krakowie
Kierownik: prof. dr hab. n. med. Maria Starzycka |
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| Summary: |
Purpose: Analysis of type
and frequency of complications after brachytherapy I125
between 1–12 months after treatment and during the
following controls.
Materials and methods: 147 persons (76 men and 71 women)
aged 23–86 years (mean 57 years), were treated in our
clinic in 1998–2001. In 43% of the cases the thickness
of the tumor was more than 8 mm and in 94% the maximum
diameter was bigger than 8.1 mm. The irradiation dose
was 80–120 Gy, mean 100 Gy.
Results: Regression and stabilization of the tumor was
achieved in 84,3% of all cases. Complications of
different type and intensity associated with
brachytherapy I125 were observed in majority of the
cases. The complications observed were: radiation
retinopathy (52%), radiation maculopathy (33,6%),
radiation optic neuropathy (25,3%), vitreous hemorrhage
(8,8%), glaucoma (20,5%) and cataract (18,5%).
Conclusions: 125I brachytherapy yields good results in
cases of uveal melanoma, however it’s associated with
post radiation complications. |
| Słowa kluczowe: |
czerniak naczyniówki,
brachyterapia, 125I, retinopatia popromienna,
makulopatia popromienna, jaskra następcza, zaćma
wikłająca. |
| Key words: |
choroidal melanoma, uveal
melanoma, brachytherapy I125, radiation
retinopathy, radiation maculopathy, radiation optic
neuropathy, consecutive glaucoma and cataract. |
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