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NR 1-3/2005
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Przepływ krwi w
mikrokrążeniu siatkówkowym u osób z postacią suchą zwyrodnienia
plamki związanego z wiekiem
Retinal capillary blood flow
in nonexudative age-related macular degeneration
Magdalena Pilas-Pomykalska1,
Izabela Nowak2, Janusz Czajkowski1,
Wojciech Omulecki2
1Z Kliniki Okulistyki Instytutu – Centrum Zdrowia
Matki Polki w Łodzi
Kierownik: prof. dr hab. n. med. Janusz Czajkowski
2Z Kliniki Chorób Oczu Katedry Chorób Oczu
Uniwersytetu Medycznego w Łodzi, Szpital Kliniczny nr 1
Kierownik: dr hab. n. med., prof. zw. Wojciech Omulecki |
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| Summary: |
Purpose: The
purpose of this study was to evaluate retinal capillary
blood flow in patients with nonexudative age-related
macular degeneration.
Material and methods: Twenty five patients with
nonexudative age-related macular degeneration and twenty
five age-matched control subjects were enrolled into the
study. Full ophthalmological examination and fluorescein
angiography were performed. Retinal blood flow was
evaluated with the Heidelberg Retina Flowmeter. Total
mean flow and mean velocity were calculated using the
technique of automatic full field perfusion image
analysis (AFFPIA).
Results: Patients with nonexudative age-related
macular degeneration revealed statistically significant
lower retinal blood flow than control subjects. In AMD
group total mean flow values were 266.89 / 272.21 AU,
while in control group were: 1.498 / 1.509 AU. Mean
velocity values were: 1.315 / 1.329 AU in AMD patients
and: 1.498 / 1.509 AU in controls.
Conclusions: The study results showed reduced
capillary retinal blood flow in patients with
age-related macular degeneration compared to normal
subjects. This retinal microcirculation impairment
suggests more generalized perfusion defect involving
both, choroidal and retinal blood flow. |
| Słowa kluczowe: |
zwyrodnienie plamki
związane z wiekiem, postać sucha zwyrodnienia plamki,
mikrokrążenie siatkówkowe, przepływ krwi. |
| Key words: |
age-related macular
degeneration, nonexudative AMD, perfusion, retinal blood
flow. |
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