|
NR 7-9/2005
|
|
|
|
|
|
|
|
|
Gęstość śródbłonka
rogówki u chorych z jaskrą
Corneal endothelial density
in glaucoma patients
Tomasz Żarnowski, Anna Łękawa, Agnieszka
Dyduch, Renata Turek, Zbigniew Zagórski
Z Katedry i I Kliniki Okulistyki im. prof. Tadeusza Krwawicza
Akademii Medycznej im. Feliksa Skubiszewskiego w Lublinie
Kierownik: prof. dr hab. n. med. Zbigniew Zagórski |
|
|
| Summary: |
Purpose: To asses
mean endothelial cell density in glaucoma patients.
Material and methods: Examinations were conducted
and registered using the Noncon Robo (Konan) non-contact
specular microscope between years 2000 and 2004, in
Tadeusz Krwawicz Chair of Ophthalmology and 1st Eye
Hospital, Medical University of Lublin. The results of
159 patients (233 eyes) with glaucoma and 37 patients
(44 eyes) with pseudoexfoliation syndrome were analyzed.
Patients, 22-91 years old, were divided into 8 groups
according to the clinical diagnosis and for each group
an adequate control group was matched. Statistical
analysis was carried out to compare the examined and
control groups using the non-parametric U Mann-Whitney
test.
Results: Corneal endothelial cell density were
significantly lower in all groups of glaucoma patients.
There was a significant reduction in cell count in
patients with chronic angle-closure glaucoma: 2333 ±
476/mm2, control group (C): 2809 ± 378/mm2,
p< 0.001), acute angle-closure glaucoma 2136 ± 620/mm2,
C. 2780 ± 384/mm2, p< 0.001, pigmentary
glaucoma 2537 ± 355/mm2, C. 3003 ± 335/mm2,
p< 0.05, juvenile glaucoma 2337 ± 277/mm2, C.
3001 ± 168/mm2, p< 0.001, primary open angle
glaucoma 2326 ± 231/mm2, C. 2779 ± 398/mm2, p< 0.001,
normal tension glaucoma 2343 ± 394/mm2, C.
2732 ± 356/mm2, p< 0.01, capsular glaucoma
2128 ± 483/mm2, C. 2753 ± 354/mm2,
p< 0.001 and in patients with pseudoexfoliation syndrome
2255 ± 299/mm2, C. 2721 ± 352/mm2,
p< 0.001.
Conclusions: Patients with glaucoma have lower
mean corneal endothelial cell density than control
groups. The density of corneal endothelial cells depends
on the type of glaucoma. |
| Słowa kluczowe: |
śródbłonek rogówki,
jaskra, bezkontaktowy mikroskop śródbłonkowy, zespół
pseudoeksfoliacji. |
| Key words: |
corneal endothelium,
glaucoma, non-contact specular microscope,
pseudoexfoliation syndrome. |
|
|
|
|
|
|
