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NR 10-12/2006
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Zespół
pseudoeksfoliacji u pacjentów wyznaczanych do operacji zaćmy
Pseudoexfoliation syndrome
in patients scheduled for cataract surgery
Iwona Obuchowska, Anna Bryl-Przybylska,
Zofia Mariak
Klinika Okulistyki Akademii Medycznej w Białymstoku
Kierownik: prof. dr hab. n. med. Zofia Mariak |
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| Summary: |
Purpose: We present
the results of a prospective investigation into the
frequency of pseudoexfoliation syndrome (XFS), age, sex,
intraocular pressure (IOP) and the type of lens opacity
in patients scheduled for cataract surgery.
Material and methods: A series of 1000
consecutive patients (604 females and 396 males in the
age from 26 to 97 years), who were admitted for cataract
surgery to the Department of Ophthalmology of Medical
University in Bialystok, were studied. All eyes were
examined with a slit-lamp biomicroscope before and after
mydriasis with 1% tropicamide and 10% phenylephrine to
find out the exfoliation. The type of cataract was
classified as mainly nuclear, cortical, posterior
subcapsular, mixed, mature or hypermature. Glaucoma was
defined as IOP ≥ 21 mmHg with optic disc and/or visual
field changes indicative of glaucoma.
Results: Exfoliation material was detected in 82
patients (8.2%). The mean age of patients with XFS (77.1
± 9.3 years) was significantly more than that of those
without XFS (65.6 ± 11.2 years), p < 0.01. The
prevalence of XFS significantly increased with advancing
age. Mature cataract and nuclear sclerosis predominated
in eyes with XFS (32.9% and 24.4%, respectively)
compared to those without XFS (24.6% and 14.2%), p <
0.05. Posterior subcapsular cataract was less common in
eyes with exfoliation (9.7%) than in eyes without it
(39.1%), p < 0.001. The mean preoperative intraocular
pressure was higher in eyes with XFS (17.8 ± 3.2 mmHg),
than in those without XFS (15.2 ± 3.8 mmHg), p < 0.01.
Glaucoma was found in 28 of 82 eyes with
pseudoexfoliation syndrome (34.1%).
Conclusions: The pseudoexfoliation syndrome
occurred much more frequently in elderly persons. PEX
has been found to be associated with higher mean
intraocular pressure, glaucoma, mature and nuclear
cataract. Posterior subcapsular cataract was less common
in patients with PEX. |
| Słowa kluczowe: |
zespół pseudoeksfoliacji,
zaćma, ciśnienie wewnątrzgałkowe, jaskra. |
| Key words: |
pseudoexfoliation syndrome,
cataract, intraocular pressure, glaucoma. |
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