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NR 10-12/2006
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Zastosowanie soli
sodowej pegaptanibu w leczeniu postaci wysiękowej zwyrodnienia
plamki związanego z wiekiem
Pegaptanib sodium in
treatment of wet AMD
Magdalena Ulińska
Z Katedry i Kliniki Okulistyki II Wydziału Lekarskiego Akademii
Medycznej w Warszawie
Kierownik: prof. dr hab. n. med. Jerzy Szaflik |
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| Summary: |
Taking into consideration
that the advanced stage of Age related Macular
Degeneration is a very common cause of social blindness
and present results of laser photocoagulation, PDT
treatment and TTT are not satisfying, it seems to be of
huge importance to look for new types of treatment, to
improve visual outcomes.
Repeated intravitreal injection of pegaptanib sodium (a
VEGF aptamer) is a modern procedure which may not only
give stabilization of visual acuity, but it may also
lead to the improvement in high percentage.
In this paper there is a short update on the
epidemiology and the symptoms of the disease and the
role of VEGF and its isoforms expression in the
development of wet AMD. The presentation of pegaptanib
sodium (Macugen®) focus on its mechanism of action.
Finally V.I.S.I.O.N. trial results are presented to show
encouraging efficacy of the procedure. |
| Słowa kluczowe: |
zwyrodnienie plamki
związane z wiekiem (AMD), neowaskularyzacja
podsiatkówkowa, sól sodowa pegaptanibu, iniekcja
doszklistkowa. |
| Key words: |
age related macular
degeneration (AMD), choroidal neovascularization,
pegaptanib sodium, intravitreal injection. |
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