|
NR 4-6/2006
|
|
|
|
|
|
|
|
|
Wpyw dopaminy
podawanej do cia kolankowatych bocznych na wzrokowe potencjay
wywoane byskiem (FVEP) kory mózgowej u szczurów
The influence of dopamine
injected into the lateral geniculate body on flash visual evoked
response in rats
Agata R. Plech1, Ewa Herba1,
Dorota Pojda-Wilczek1, Katarzyna
Makowiecka-Obidzińska1, Stefan M. Pojda1,
Andrzej Plech2
1 Z Katedry i Oddziału Klinicznego Okulistyki w
Bytomiu ¦l±skiej Akademii Medycznej w Katowicach
Kierownik: prof. dr hab. n. med. Stefan M. Pojda
2 Z Katedry i Zakładu Farmakologii w Zabrzu-Rokitnicy
¦l±skiej Akademii Medycznej w Katowicach
Kierownik: prof. dr hab. n. med. Ryszard Brus |
|
|
| Summary: |
Purpose: Numerous
neurotransmitters and neuromodulators operating on all
levels of the visual system, influence the parameters of
cortical evoked response. The aim of this study was to
find the influence of dopamine (DA) injected into the
lateral geniculate body (nucleus) on flash visual evoked
response (FVEP).
Material and methods: The experiments were
performed on adult Wistar rats. They were implanted with
1 caniula conducted into the lateral geniculate body and
2 electrodes: active under the skull on dura mater in
occipital region of brain and reference one on the skull
in the interorbital region. FVEPs curve before and after
injection into the lateral geniculate body 0.9% NaCl and
DA were analyzed.
Results: DA in the lateral geniculate body causes
increasing latency and amplitude of FVEP peaks.
Conclusions: Dopamine in the lateral geniculate body can
improve visual perception in the occipital cortex. |
| Słowa kluczowe: |
wzrokowe potencjały
wywołane, ciała kolankowate boczne, dopamina, szczury. |
| Key words: |
visual evoked potentials,
lateral geniculate body, dopamine, rats. |
|
|
|
|
|
|
