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NR 4-6/2006
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Zastosowanie terapii
fotodynamicznej w leczeniu ograniczonych naczyniaków naczyniówki
Photodynamic therapy of
circumscribed choroidal hemangioma
Agnieszka Kubicka-Trz±ska, Bożena
Romanowska-Dixon
Z Katedry i Kliniki Okulistyki Collegium Medicum Uniwersytetu
Jagiellońskiego w Krakowie
Kierownik: dr hab. n. med. Bożena Romanowska-Dixon |
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| Summary: |
Purpose: To
evaluate efficacy of photodynamic therapy (PDT) with
verteporfin in treatment of posterior pole symptomatic
circumscribed choroidal hemangiomas.
Material and methods: Four patients (3 men and 1
woman), 15-55 years old (mean age: 29 years) with
circumscribed choroidal hemangiomas of the posterior
pole, were examined. The hemangiomas localization were
subfoveal in one patient, extrafoveal in 2 cases, and
juxtapapillar in one case. The diagnosis of choroidal
hemangioma was established on the base of clinical
examination, A and B – scan ultrasound imaging, Doppler
ultrasonography, fluorescein and indocyanine angiography
results. Tumour thickness before treatment ranged from
2.3-3.6 mm (mean thickness: 2.8 mm). One course of PDT
with verteporfin was performed in 3 cases, while in one
patient PDT was performed four times.
Results: In a follow-up period which range from 3
to 14 months (mean 5.7 months) all cases demonstrated
clinical features of lesion regression with a reduction
of thickness on ultrasonography and choroidal
vasculature on angiograms. Visual acuity was improved in
3 patients (from 1 to 4 lines on Snellen charts), or
remained stable in 1 case.
Conclusions: Our preliminary results indicate
that PDT with verteporfin is a safe and effective method
of treatment for circumscribed choroidal hemangiomas,
especially in patients with posterior pole location of
the tumour. |
| Słowa kluczowe: |
ograniczony naczyniak
naczyniówki, terapia fotodynamiczna. |
| Key words: |
circumscribed choroidal
haemangiona, photodynamic therapy. |
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