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NR 4-6/2006
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Współczesne poglądy
na temat olbrzymiokomórkowego zapalenia tętnic
A new approach towards giant
cell arteritis
Iwona Obuchowska, Zofia Mariak
Z Kliniki Okulistyki Akademii Medycznej w Białymstoku Kierownik:
prof. dr hab. n. med. Zofia Mariak |
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| Summary: |
Giant cell arteritis is a
rare systemic vasculitis affecting large- and
medium-sized arteries. Focal arteries lesions, include
mononuclear cells infiltration of the vessel wall with
giant cell formation. It is a disease of elderly persons
and can result in a wide variety of systemic,
neurological and ophthalmic complications, due to
ischemia. The incidence of visual loss and ocular
involvement varies between 14-88%, but one of the most
common and severe complications is anterior ischemic
optic neuropathy. The other ocular ischemic lesions
include: central retinal artery occlusion, choroidal
ischemia, diplopia, ocular motor paresis, anterior
uveitis, cataract, ocular hypotony, corneal oedema and
ulcerations, episcleritis and anterior scleritis,
orbital cellulitis and pseudotumor. Because giant cell
arteritis is potentially blinding disease, early
diagnosis and immediate treatment with high dose
corticosteroids may prevent further damage to the
affected eye and prevent visual loss in the opposite eye.
The purpose of this review is to revise established
knowledge and to highlight the recent developments in
diagnosis and management of giant cell arteritis. |
| Słowa kluczowe: |
olbrzymiokomórkowe
zapalenie tętnic, przednia niedokrwienna neuropatia
nerwu wzrokowego, biopsja tętnicy skroniowej. |
| Key words: |
giant cell arteritis,
anterior ischemic optic neuropathy, temporal artery
biopsy. |
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