|
NR 7-9/2006
|
|
|
|
|
|
|
|
|
Neuropatia
popromienna po brachyterapii czerniaka naczyniówki
Radiation optic neuropathy
after the brachytherapy of the uveal melanoma
Iwona Szu¶cik, Bożena Romanowska-Dixon,
Anna Markiewicz, Arkadiusz Pogrzebielski, Barbara Jakubowska
Z Katedry i Kliniki Okulistyki Collegium Medicum Uniwersytetu
Jagiellońskiego w Krakowie
Kierownik: dr hab. n. med. Bożena Romanowska-Dixon |
|
|
| Summary: |
Purpose: The
evaluate the frequency of radiation of the optic
neuropathy (RON) and its influence on visual acuity in
patients with choroidal melanoma treated by
brachytherapy.
Material and methods: We analyzed 583 patients
with choroidal melanoma, treated with ruthenium (106Ru)
or iodine (125I) plaques in Ophthalmology Department of
Jagiellonian University, between 1996 and 2004 year. The
frequency of RON, its influence on loss of vision,
according to a kind of the used isotope, tumor size and
location were analyzed. Diagnosis of RON was established
on the base of characteristic symptoms in the eye fundus.
Results: The frequency of RON was significantly
higher in cases treated by 125I vs 106Ru (14% vs 8,2%,
p=0.0014), in cases of tumors located in the posterior
pole (31,3%, p=0.012), and in cases of tumor thickness
3-8 mm (27,5%, p=0.033). In most of patients we observed
major deterioration of visual acuity.
Conclusions: The radiation of the optic
neuropathy was seen often after iodine BT, tumors
located in the posterior pole of fundus, with thickness
3-8 mm. |
| Słowa kluczowe: |
czerniak naczyniówki,
brachyterapia, neuropatia nerwu wzrokowego. |
| Key words: |
choroidal melanoma,
brachytherapy, optic neuropathy. |
|
|
|
|
|
|
