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NR 7-9/2006
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Przerzuty raka
gruczołu piersiowego do naczyniówki – obserwacje kliniczne 18
przypadków
Choroidal metastases from
breast cancer – clinical observations of 18 cases
Agnieszka Kubicka-Trz±ska, Bożena
Romanowska-Dixon
Z Katedry i Kliniki Okulistyki Collegium Medicum Uniwersytetu
Jagiellońskiego w Krakowie
Kierownik: dr hab. n. med. Bożena Romanowska-Dixon |
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| Summary: |
Purpose: To present
clinical picture and results of treatment of breast
carcinoma metastases to choroid.
Material and methods: Eighteen females (26 eyes),
age: 31-70 years old; mean age: 50.5 ±14.5 years with
breast carcinoma choroidal metastases were enrolled in
this study. Choroidal metastases occurred 1 month to 288
months, mean: 64 ±33 months, after primary tumors had
been diagnosed. In all cases basic eye examination with
ultrasonography as well as fluorescein and indocyanine
green angiography in some patients, were performed.
Method of treatment was applied according to tumor size
and its localization; 106Ru plaque therapy
was used in 8 cases, 125I in 2,
transpupillary therapy (TTT) in 8, 106Ru +
TTT (“sandwich method”) in 4, teleradiotherapy in 3 and
enucleation was performed in one case. The follow-up
period ranged from 6 months to 5 years, mean 15.3 ±7.7
months.
Results: Unilateral choroidal metastases were
present in 10 patients and bilateral in 8. Single
metastatic lesions were detected in 15 patients and
multiple in 3. Tumors thickness measured by
ultrasonography ranged from 1.2 to 16.2 mm. After
therapy regression of tumors was noted in 7 eyes (10
tumors), among which in four eyes (7 tumors) total
regression was observed. Stabilization was found in 4
eyes (4 tumors) and progression in other 4 eyes (4
lesions).
Conclusions: Tumor size, its localization and
general patient condition are the main factors deciding
about the method in treatment of choroidal metastases.
Plaque therapy and transpupillary thermotherapy are
effective methods of treatment in majority of metastatic
tumors. They induce tumor regression and in some cases
they may provide improvement in visual acuity. |
| Słowa kluczowe: |
przerzuty do naczyniówki,
rak piersi. |
| Key words: |
choroidal metastases,
breast carcinoma. |
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