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NR 7-9/2006
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Ocena wybranych
wykładników odpowiedzi immunologicznej u dzieci z objawami
zapalenia części pośredniej błony naczyniowej
Estimation of immunological
markers in children with intermediate uveitis symptoms
Anna Turno-Kręcicka1, Bożena
Polańska2, Maria Turska1, Anna Barć1
1 Z Katedry i Kliniki Okulistycznej Akademii
Medycznej we Wrocławiu
Kierownik: prof. dr hab. n. med. Maria Hanna Niżankowska
2 Z Katedry Propedeutyki Pediatrii i Kliniki
Immunologii i Reumatologii Wieku Dziecięcego Akademii Medycznej
we Wrocławiu
Kierownik: prof. dr hab. n. med. Adam Jankowski |
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| Summary: |
Purpose: The
purpose of this study was to estimate markers of
immunological response in the blood of children with
intermediate uveitis.
Material and methods: The records of 13 children
(26 eyes), aged 10-17 years, with idiopathic
intermediate uveitis were reviewed. In all cases
indicators of inflammation and immunological response
parameters were analyzed during the active stage of the
disease.
Results: In almost all patients ((90%) with
intermediate uveitis disturbances in the level and
activity of lymphocyte system, were detected. There were
also nonspecific changes in immunoglobulins level in all
patients, in 31% in more then one class of
immunoglobulins. Chemiluminescence of phagocytic cells
were reduced in more than 50% of children, and increase
in their phagocytic activity was observed in 62% of
patients. Circulating immune complexes were present in
50% of cases.
Conclusions: The study presents data supporting
the theory of autoimmunological background of the
intermediate uveitis. |
| Słowa kluczowe: |
zapalenie części
pośredniej błony naczyniowej, torbielowaty obrzęk
plamki, zapalenie naczyń siatkówki, układ odpornościowy,
limfocyty, patogeneza. |
| Key words: |
intermediate uveitis,
cystoid macular oedema, retinal vasculitis, immune
system, lymphocytes, pathogenesis. |
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