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NR 7-9/2006
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Przerzuty
nowotworowe do naczyniówki gałki ocznej. Przegląd metod leczenia
ze szczególnym uwzględnieniem radioterapii
Choroidal metastases of
malignancies. Review of treatment methods with special regard to
application of radiotherapy
Beata Sas-Korczyńska1, Bożena Romanowska
Dixon2, Jan Skołyszewski1, Jan Lesiak3
1 Z Kliniki Radioterapii Centrum Onkologii –
Instytutu im. M. Skłodowskiej-Curie w Krakowie
Kierownik: prof. dr hab. n. med. Jan Skołyszewski
2 Z Kliniki Okulistyki Collegium Medicum Uniwersytetu
Jagiellońskiego w Krakowie
Kierownik: dr hab. n. med. Bożena Romanowska-Dixon
3 Z Zakładu Fizyki Medycznej Centrum Onkologii –
Instytutu im. M. Skłodowskiej-Curie w Krakowie
Kierownik: prof. dr hab. Michał Waligórski |
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| Summary: |
Choroidal metastases are
developed in 4 – 12% of patients with solid malignancies.
Typical symptoms are loss of visual acuity or visual
field, photophobia and floaters.
In therapy of choroidal metastases are used following
methods: surgery, laser photocoagulation, radiotherapy,
and systemic treatment (anti-neoplastic chemotherapy or
hormonotherapy).
At choice of method of treatment it is taking not only
features associate with choroidal metastases (as size,
shape, number of changes and localization) but also:
performance status of patient and the presence of
metastases in any sites.
The purpose of this paper is the review of treatment
methods of choroidal metastases with special regard to
application of radiotherapy.
Radiotherapy is a conservative method of treatment, and
it is used as brachytherapy or external beam irradiation
(teleradiotherapy). Brachytherapy is recommended in case
of single change, with base diameter below 18 mm. The
positive results are observed in 90% cases.
Teleradiotherapy is used in metastatic tumours which
size exceed possibility successfully using of
brachytherapy, and in case of multiple foci of choroidal
changes, and metastases bilaterally localized. 70 – 89%
patients developed regression of choroidal metastases
after external beam irradiation. The preservation of
bulbus oculi is observed in 98% patients.
Presented paper showed application of methods of
brachytherapy used in Ophthalmological Department of
Jagiellonian University, and technique of
teleradiotherapy used in Radiotherapy Department of
Oncology Centre in Krakow, which are used in treatment
of choroidal metastases. |
| Słowa kluczowe: |
przerzuty do naczyniówki,
brachyterapia, teleradioterapia. |
| Key words: |
choroidal metastases,
brachytherapy, teleradiotherapy. |
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