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NR 10-12/2007
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Ocena stanu
śródbłonka rogówki u pacjentów z cukrzycą
Evaluation of corneal
endothelium morphology in diabetic patients
Agata Wesołek-Czernik, Joanna Bartela,
Ewa Zamojska, Wojciech Omulecki
Z Katedry i Kliniki Chorób Oczu Uniwersytetu Medycznego w Łodzi
Kierownik: prof. dr hab. n. med. Wojciech Omulecki |
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| Summary: |
Purpose: To
evaluate the influence of diabetes mellitus and type of
hipoglicemic therapy on corneal endothelium cell
morphology.
Material and methods: In 68 diabetic patients’
eyes with non proliferative diabetic retinopathy (29
males and 39 females), corneal endothelium was studied.
Patients age was between 50 and 82 years (mean 63.28).
As age-matched control group we analyzed 58 eyes of non
diabetic patients. Corneal endothelium density,
percentage of corneal endothelium hexagonal cells,
average size of corneal endothelium cells and corneal
thickness were imaged by non– contact specular
microscope TOPCON SP-2000P.
Results: The mean corneal endothelium cell
density was: 2467 cells/mm2 in diabetic patients, and
2573 cells/ mm2 in control group. The mean percentage of
corneal endothelium hexagonal cells was: 55.3% in
diabetic patients treated with insulin and 52.9% in
diabetic patients treated with oral antidiabetic drugs,
and 54.4% in the control group. The mean size of corneal
endothelium cells was: 414.6 μm2 in diabetic patients,
and 395.9 μm2 in the control group. The mean corneal
thickness was: 0.556 mm in diabetic patients and 0.545
mm in the control group.
Conclusions: Corneal endothelium was thicker in
diabetic patients than in non diabetic patients. The
duration of diabetes mellitus had no influence on
corneal endothelium cell morphology. Diabetic patients
treated with oral antidiabetic drugs had larger
percentage of hexagonal cells than those treated with
insulin. |
| Słowa kluczowe: |
śródbłonek rogówki,
pacjenci z cukrzycą. |
| Key words: |
corneal endothelium,
diabetic patients. |
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