NR 1-3/2007

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Ocena wyników leczenia mięsaka mięśni prążkowanych oczodołu u dzieci

Evaluation of the results of treatment orbital rhabdomyosarcoma in children

Barbara Chipczyńska, Mirosława Grałek, Wojciech Hautz, Krystyna Kanigowska, Beata Kocyła-Karczmarewicz, Agnieszka Trzebicka, Beata Kępa

Z Kliniki Okulistyki Instytutu „Pomnik-Centrum Zdrowia Dziecka” w Warszawie
Kierownik: prof. dr hab. n. med. Mirosława Grałek

Summary: Purpose: To estimate the state of the vision organ in the children treated for orbital rhabdomyosarcoma. Rhabdomyosarcoma (RMS) is the most common primary malignant orbital tumor in children. RMS usually manifest clinically as rapidly progressive exophthalmus and displacement of the globe. The diagnosis is based on biopsy, CT and MR images. The treatment includes radiation, chemotherapy, and surgery.
Material and methods: The retrospective review of data of 14 children between 0 and 11 years old with rhabdomyosarcmoa of orbit. After a biopsy, with precedent CT or MRI, all patients were treated with chemotherapy including or not including radiotherapy.
Results: 3 children died, orbital exentaration was necessary because of tumor recurrence in 3 cases, 8 children remained healthy (without recurrent disease).
Conclusions: Fast diagnosis using CT, MRI and the result of biopsy, have a positive influence on the effect of neoplastic treatment and prognosis.
Słowa kluczowe:  mięsak mięśni prążkowanych, oczodół, dzieci, objawy kliniczne, leczenie.
Key words: orbital rhabdomyosarcoma, orbit, children, clinical symoptoms, treatment.



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