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NR 1-3/2007
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Neurohormonalna
regulacja dynamiki cieczy wodnistej jako podstawa farmakoterapii
jaskry.
Czę¶ć II – Odpływ cieczy wodnistej
Neuro-hormonal regulation of
aqueous humor dynamics as the basis of glaucoma pharmacotherapy.
Part II – Aqueous humor outflow
Barbara Terelak-Borys, Iwona Liberek
Z Kliniki Okulistyki Centrum Medycznego Kształcenia
Podyplomowego w Warszawie
Kierownik: dr n. med. Iwona Liberek |
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| Summary: |
The aim of this article is
to present current opinion on aqueous humor dynamics
regulation and antiglaucoma drugs mechanisms of action.
Pharmacotherapy of glaucoma is based mainly on
neuro-hormonal processes controlling aqueous humor
dynamics. Systemic hormones as well as local hormones
and autonomic nervous system mediators are involved in
the processes of aqueous humor formation and drainage.
Antiglaucoma medications act mainly through activation
or inhibition of these systems’ receptors, helping to
decrease aqueous humor production or improve aqueous
humor outflow. In this article (part 2) we describe two
groups of antiglaucoma medications (parasympathicomimetics,
prostaglandin analogues), inhibiting the aquoeus humor
outflow and mechanisms of their hypotensive effect in
the eye. |
| Słowa kluczowe: |
dynamika cieczy wodnistej,
odpływ drog± konwencjonaln±, odpływ drog±
naczyniówkowo-twardówkow±, farmakoterapia jaskry,
analogi prostaglandyn, parasympatykomimetyki. |
| Key words: |
aqueous humor dynamics,
conventional outflow, uveoscleral outflow,
pharmacotherapy of glaucoma, prostaglandin analogues,
parasympathicomimetics. |
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