NR 1-3/2007

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Objawy ogólne i zmiany oczne w układowym toczniu rumieniowatym

General and ocular symptoms in systemic lupus erythematosus (SLE)

Joanna Brydak-Godowska

Z Katedry i Kliniki Chorób Oczu Akademii Medycznej w Warszawie
Kierownik: prof. dr hab. n. med. Dariusz Kęcik

Summary: Systemic lupus erythematosus (SLE) is a chronic, immunologically mediated inflammatory connective tissue disorder with manifestations including various body organs (joints, pleura, pericardium, kidneys, brain, skin), caused by accumulation of immune complexes. According to epidemiological data SLE affects 0.12% of the population worldwide, while in Poland the number of reported cases is c. 60 000 – 80 000. SLE may also involve the eye. Anterior segment findings include keratoconjunctivitis sicca, keratitis and scleritis.
Retinal manifestations of SLE are cotton wool spots, hemorrhage and vasculitis.
The ARA (American Rheumatism Association), criteria are used in establishing the diagnosis of SLE. Although the ocular symptoms are not included in the ARA criteria, they may be initial findings and precede other manifestations of SLE.
Słowa kluczowe:  układowy toczeń rumieniowaty, kryteria ARA, zmiany oczne.
Key words: systemic lupus erythematosus, ARA criteria, ocular changes.



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