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NR 4-6/2007
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Przezźrenicza
termoterapia w leczeniu wysiękowej postaci zwyrodnienia plamki
związanego z wiekiem
Transpupillary thermotherapy
in exudative age-related macular degeneration
Agnieszka Kubicka-Trząska, Maria
Starzycka, Ewa Ortyl, Alina Górniak-Bednarz, Izabella
Karska-Basta
Z Kliniki Okulistyki i Onkologii Okulistycznej Katedry
Okulistyki Collegium Medicum Uniwersytetu Jagiellońskiego w
Krakowie
Kierownik: dr hab. n. med. Bożena Romanowska-Dixon |
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| Summary: |
Purpose: Assessment of TTT
results in patients with exudative age-related macular
degeneration.
Material and methods: The study comprised of 65 patients
(73 eyes), in age 50-84 years (average age-75 yrs). The
diagnosis of exudative AMD was established on the basis
of fundus examination and fluorescein angiography (FA)
and in some cases on indocyanine green angiography. The
baseline visual acuity (VA) ranged from counting fingers
at 50 cm to 0.8. In 31 (42.5%) eyes occult CNV, in 11
(15%) minimally classic CNV and in 31 (42.5%) eyes
predominantly classic CNV were observed. Subfoveal CNV
was present in 70 (95.9%) eyes and perifoveal in 3
(4.1%). TTT was delivered using a diode laser at 810 nm
wavelength, a spot size of 1.2 to 4.5 mm and a duration
of 60 seconds for each spot with power settings between
320 – 800 mW. Follow-up examinations were carried out
every 10-12 weeks. In cases with persistent leakage from
CNV in late frames of FA a retreatment was performed.
The follow-up period ranged from 6 to 28 months (average
– 9.8 months).
Results: Visual acuity improved in 22 (30.1%) eyes,
stabilized in 34 (46.6%) and deteriorated in 17 (23.3%).
Fluorescein angiography showed no CNV leakage in 58
(79.5%) eyes. In 56 (71.8%) with regression of leakage
in fluorescein angiography improvement or stabilization
of visual acuity was detected. Subretinal haemorrhages
after TTT were observed in 4 eyes (5.5%). At the end of
the follow-up period fibrosis of CNV was detected in 12
eyes (16.4%).
Conclusions: TTT is effective and safe method of
treatment of occult and classic CNV in a course of wet
AMD. In a majority of cases TTT results in total or
partial regression of CNV and stabilization of visual
acuity. |
| Słowa kluczowe: |
przezźrenicza termoterapia,
wysiękowa postać zwyrodnienia plamki związanego z
wiekiem, neowaskularyzacja naczyniówkowa. |
| Key words: |
transpupillary
thermotherapy, exudative age-related macular
degeneration, choroidal neovascularization. |
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