NR 4-6/2007

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Zastosowanie iniekcji octanu triamcinolonu w leczeniu torbielowatego obrzęku plamki w przebiegu zakrzepu żyły środkowej siatkówki

Inhtravitreal triamcinolone acetonide injections in the treatment of cystoid macular edema due to the central or branch retinal vein occlusion

Anna Lubczyńska, Jarosław Kocięcki

Z Katedry i Kliniki Okulistyki Akademii Medycznej w Poznaniu
Kierownik: dr hab. n. med. Jarosław Kocięcki

Summary: Purpose: To appoint the most adequate follow-up parameter and to find the most reliable scheme of intravitreal TA injections in CME treatment in the course of CRVO and BRVO.
Material and methods: 18 eyes treated with intravitreal injection of 4 mg (in 0.1 ml) of crystalline TA.
Results: There was improvement of BCVA for distance noticed in 38.9% of eyes and for near in 44.4% of cases. There was statistically significant difference in retinal thickness outcomes measured at baseline and at the end of the follow-up by both OCT and RTA. No correlation of BCVA changes and retinal thickness changes measured in OCT and RTA was found.
Conclusions: The intravitreal TA injections should be considered as an effective method. Foveal morphology and thickness analysis performed by OCT is the most adequate method in follow-up monitoring of intravitreal TA injections in CME treatment in non-ischemic CRVO or BRVO. Central retinal thickness measured by RTA and FA changes analysis are alternative monitoring methods. Dosage of 4mg TA in 0.1 ml seems to be sufficient. In cases of CME recurrence of subsequent intravitreal injection in the first 6 month after initial injection seems to be unnecessary.
Słowa kluczowe:  zakrzep żyły środkowej siatkówki, zakrzep gałęzi żyły środkowej siatkówki, torbielowaty obrzęk plamki, octan triamcinolonu.
Key words: central retinal vein occlusion, branch retinal vein occlusion, cystoid macula edema, triamcinolone acetonide.



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