|
NR 4-6/2007
|
|
|
|
|
|
|
|
|
Obrazowanie
autofluorescencji dna oka u chorych z chorob± Stargardta i
fundus flavimaculatus
Fundus autofluorescence
imaging in patients with Stargardt dystrophy and fundus
flavimaculatus
Joanna Dolar-Szczasny, Jerzy Mackiewicz,
Barbara Biziorek, Zbigniew Zagórski
Z Katedry i I Kliniki Okulistyki Akademii Medycznej w Lublinie
Kierownik: dr hab. n. med. Tomasz Żarnowski |
|
|
| Summary: |
Purpose: To identify
patterns of fundus autofluorescence (AF) in patients
with Stargardt dystrophy and fundus flavimaculatus.
Material and methods: 20 patients in age 7 to 47 years
with Stargardt dystrophy and fundus flavimaculatus, were
examined. Ophthalmic evaluation included nonstandarized
Snellen visual acuity,complete ophthalmic examination,
fluorescein angiography and color fundus photographs.
The autofluorescence images were obtained using a
confocal scanning laser ophthalmoscope HRA2.
Results: In 15 patients lack or decreased AF signal in a
foveal region with punctate diffuse spots with increased
and decreased AF signal extending far from the macular
region were observed. In 4 patients apart from lack of
the AF signal in the central area punctate spots were
restricted to the macular region. In 1 patient AF image
was copletely normal.
Conclusions: Autofluorescence imaging allows for
evaluation of the area with changes on the RPE level
typical for this disease and is helpful, noninvasive
examination for diagnostic process in such patients. A
wide variation in clinical phenotype can occur in
patients with Stargardt disease and fundus
flavimaculatus. Obtained different fenotypes in
autofluorescence imaging may correlate with different
clinical types of this disease, described in the
literature. |
| Słowa kluczowe: |
choroba Stargardta, fundus
flavimaculatus, autofluorescencja dna oka, konfokalny
skaningowy oftalmoskop laserowy. |
| Key words: |
Stargardt disease, fundus
flavimaculatus, fundus autofluorescence, confocal
scanning laser ophthalmoscope (CSLO). |
|
|
|
|
|
|
