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NR 7-9/2007
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Wpływ ciąży na
progresję retinopatii cukrzycowej
The influence of pregnancy
on progression of diabetic retinopathy
Ewa Proniewska-Skrętek, Renata Zalewska,
Paweł Kraśnicki, Barbara Zarzycka1, Wiesław Zarzycki1, Zofia
Mariak, Maria Górska
Z Kliniki Okulistyki Akademii Medycznej w Białymstoku
Kierownik: prof. dr hab. n. med. Zofia Mariak
1Z Kliniki Endokrynologii Akademii Medycznej w Białymstoku
Kierownik: prof. dr hab. n. med. Maria Górska |
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| Summary: |
Purpose: Pregnancy
is considered an important risk factor of the
development and progression of diabetic retinopathy
(DR). The aim of the study was to assess whether retinal
changes tend to progress during pregnancy in women with
type 1 diabetes.
Material and methods: 136 women with type 1
diabetes were enrolled to this 3 years prospective study.
The patients were divided according to White’s scale
into the following classes: B (n=76), C (n=34), D
(n=24), R (n=2). Before conception and during pregnancy
the patients were treated with intensive insulin therapy
to achieve optimal metabolic control. Ophthalmic
examination was performed before planned conception, in
each trimester of the pregnancy and after delivery.
Results: No pathologies were discovered with
fundoscopy in all the women belonging to class B, in 22
women from class C and in 4 women from class D. No
progression of diabetic retinopathy was observed during
the entire period of observation in 12 women from class
C and in 20 from class D with nonproliferative DR in the
first examination. In 3 women from class C progression
of DR were observed in the second trimester with partial
improvement after delivery. Visual acuity in these
patients also deteriorated. Proliferative DR diagnosed
in 2 patients from class R at the beginning of the
observation, progressed during the pregnancy to diminish
after delivery.
Conclusions: Pregnancy does not influence
significantly the progression of pre–existing diabetic
retinopathy, provided that proper metabolic control is
achieved and patients are subject to systematic
ophthalmological control. |
| Słowa kluczowe: |
retinopatia cukrzycowa,
ciąża. |
| Key words: |
diabetic retinopathy,
pregnancy. |
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