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NR 7-9/2007
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Neuropatia jaskrowa
i neuropatia w przebiegu stwardnienia rozsianego – wspólne
elementy patogenezy?
Glaucoma neuropathy and
neuropathy in multiple sclerosis – common elements of
pathogenesis?
Irmina Jankowska-Lech1,
Barbara Terelak-Borys1, Iwona Grabska-Liberek1,
Witold Palasik2
1Z Kliniki Okulistyki Centrum Medycznego Kształcenia
Podyplomowego w Warszawie
P.o. kierownik: dr n. med. Iwona Grabska-Liberek
2Z Kliniki Neurologii Centrum Medycznego Kształcenia
Podyplomowego w Warszawie
Kierownik: dr hab. n. med. U. Fiszer |
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| Summary: |
The optic neuropathy in
multiple sclerosis and glaucoma neuropathy are very
common ophthalmological diseases. Multiple sclerosis
/MS/ is the chronic inflammatory central nervous system
demyelinisation disease with an autoimmunological
ethiology. The last investigation of multiple sclerosis
indicate the molecular and cellular autoimmunisation
aspects. Te role of vasoactive factors is underlines in
its pathogenesis which also suggests the common elements
of glaucoma and MS pathogenesis. The over expressed
vasoconstrictive mechanisms in both diseases can conduct
to optic nerve injury.
The aim of this study is evaluation of the optic disc
morphological changes in sclerosis multiplex patients
/MS/ with or without neuritis optica in anamnesis in
glaucoma “remodeling” aspects.
Material and methods: We present two patients
with coexsist sclerosis multiplex and glaucoma
neuropathy, which underwent retrobulbar neuritis.
Conclusion: Coexistance of glaucoma neuropathy
and multiple sclerosis neuropathy may indicate common
elements of glaucoma and SM pathogenesis. The authors
recommend precise morphological optic disc evaluation in
multiple sclerosis patients because glaucoma neuropathy
may appear. |
| Słowa kluczowe: |
neuropatia jaskrowa,
stwardnienie rozsiane, mechanizmy naczynioskurczowe,
endotelina–1. |
| Key words: |
glaucoma neuropathy,
multiple sclerosis, vasoconstrictive mechanisms,
endothelin–1. |
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