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NR 7-9/2007
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Rola chemokin w
schorzeniach narządu wzroku.
Część II.
Udział chemokin w chorobach narządu wzroku
The role of chemokines in
ocular diseases.
Part II.
Participation of chemokines in ocular diseases
Roman Malesiński1, Małgorzata
Mrugacz2, Alina Bakunowicz-Łazarczyk2
1Z Oddziału Chorób Oczu Wojewódzkiego Szpitala
Zespolonego w Białymstoku
Ordynator: dr n. med. Bogusław Żywalewski
2Z Kliniki Okulistyki Dziecięcej Akademii Medycznej w
Białymstoku
Kierownik: prof. dr hab. n. med. Alina Bakunowicz-Łazarczyk |
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| Summary: |
The chemokines are family
of ca. 50 chemotactic cytokines produced by leucocytes
and tissue cells, which regulate and stimulate
leucocytes migration. Dysregulation of this process is
apparent in chronic inflammation, allergic eye disease,
corneal graft rejection, proliferative
vitreoretinopathies and age-related macular degeneration.
Antagonists of chemokine receptors have demonstrated
anti–inflammatory and antiviral activity and may
represent new generations of therapeutic agents. |
| Słowa kluczowe: |
chemokiny, receptory
chemokin, choroba autoimmunizacyjna. |
| Key words: |
chemokines, chemokine
receptors, autoimmune disease. |
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