|
NR 1-3/2008
|
|
|
|
|
|
|
|
|
Zastosowanie badania
grubości włókien nerwowych siatkówki – GDx u pacjentów ze
stwardnieniem rozsianym
Application of retinal
nerves fiber layer examination – GDx in patients with multiple
sclerosis
Irmina Jankowska-Lech1,
Barbara Terelak-Borys1, Iwona Grabska-Liberek1,
Jaromir Wasyluk1, Witold Palasik2
1Z Kliniki Okulistyki Centrum Medycznego Kształcenia
Podyplomowego w Warszawie
P.o. kierownik: dr n. med. Iwona Grabska-Liberek
2Z Kliniki Neurologii i Epileptologii Centrum
Medycznego Kształcenia Podyplomowego w Warszawie
Kierownik: prof. nadzw. dr hab. n. med. Urszula Fiszer |
|
|
| Summary: |
Purpose: The
purpose of our study is to evaluate retinal fiber layer
thickness with scanning polarymetry laser (GDx), in
patients suffering from SM with or without optic nerve
symptoms. Multiple sclerosis proceeds to
neurodegenerative changes and commonly appears with
retrobulbar optic nerve damage. Examination of retinal
nerves fiber layer examination with scanning laser
polarymetry (GDx) enables to perform quantitative
evaluation of retinal nerves fiber layer thickness
within the area around the optic nerve disc.
It finds application in diagnosis and monitoring of
glaucoma, however its usefulness as a tool evaluating
optic nerve in multiple sclerosis, has not been proved
yet.
Materials and methods: Subjects diagnosed with
multiple sclerosis (SM) were divided into 2 groups.
First group was comprised of subjects, who suffered from
at least one episode of retrobulbar neuritis, in at
least one eye. Second group was made up of 8 subjects
with no history of retrobulbar neuritis. Retinal nerves
fiber layer thickness was measured with scanning
polarymetry laser (GDx).
Results: Symptoms of retinal nerves fiber layer
damage, were discovered with GDx significantly more
common in first group (70% vs 18.75% accordingly).
Conclusions: Moreover, we stated that evaluation
with scanning polarymetry laser might be precious method
in discovering retinal nerves fiber layer damage in the
course of multiple sclerosis.
Presence of defects in retinal nerves fiber layer in
patients suffering from multiple sclerosis with no
history of retrobulbar neuritis may suggest subclinical
damage of optic nerve. |
| Słowa kluczowe: |
warstwa włókien nerwowych
siatkówki, skaningowa laserowa polarymetria,
stwardnienie rozsiane. |
| Key words: |
retinal nerves fiber layer,
scanning laser polarymetry, multiple sclerosis. |
|
|
|
|
|
|
