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NR 1-3/2008
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Analiza wybranych
neonatalnych czynników ryzyka rozwoju retinopatii wcześniaków
Analysis of some of the
possible neonatal risk factors of development of retinopathy of
prematurity
Anna Niwald1, Andrzej
Piotrowski2, Mirosława Grałek1,3
1Z Kliniki Okulistyki Dziecięcej Katedry Pediatrii
Zabiegowej Uniwersytetu Medycznego w Łodzi
P.o. kierownik: dr n. med. Anna Niwald
2Z Oddziału Klinicznego Intensywnej Terapii i
Anestezjologii Uniwersytetu Medycznego w Łodzi
Kierownik: dr hab. n. med. Andrzej Piotrowski
3Z Kliniki Okulistyki Instytutu – Pomnika ,,Centrum
Zdrowia Dziecka’’ w Warszawie
Kierownik: prof. dr hab. n. med. Mirosława Grałek |
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| Summary: |
Summary: Purpose:
The aim of the study was to evaluate some of the
possible risk factors for retinopathy of prematurity
(ROP) treated with laser photocoagulation or
cryocoagulation.
Material and methods: The study comprised 71
preterm infants with ROP needing treatment and 118
prematures without ROP or with ROP requiring no
treatment, as a control group. All infants were born
with gestational age ≤ 32 weeks and birth weight ≤
1500g. The perinatal variables, including some of
clinical data, the length of mechanical ventilation as
well as continous positive airway pressure (CPAP),
duration of total parenteral nutrition and some of
laboratory data were analyzed, to evaluate their
correlation with the development of ROP.
Results: Gestational age before 28 weeks (OR =
5.11), episodes of convulsiones (OR = 2.15), mechanical
ventilation for more than 20 days (OR = 5.86) and > 30
days (OR = 7.47), CPAP for more than 5 days (OR = 4.15)
and >10 days (OR = 2.84), total parenteral nutrition for
more than 10 days (OR = 7.84) and >20 days (OR = 9.02)
and elevated peak of alanine aminotransferase (AlAT)
levels (OR = 3.17) were significant risk factors for ROP
requiring treatment.
Conclusions: The opthalmic examination for
retinopathy of prematurity requiring laser
photocoagulation or cryocoagulation should be obligatory
for prematures born ≤ 32 weeks of gestational age, with
birth weight ≤ 1500 g.The frequency of the consecutive
ophthalmic examinations depends on the severity of
prematurity and on the presence and intensification of
the risk factors for ROP. |
| Słowa kluczowe: |
wcześniactwo, retinopatia
wcześniaków, czynniki ryzyka. |
| Key words: |
prematurity, retinopathy
of prematurity, risk factors. |
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