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NR 1-3/2008
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Oczne czynniki
ryzyka zwyrodnienia plamki związanego z wiekiem (AMD). Część I
Eye’s risk factors in age –
related macular degeneration (AMD). Part I
Monika Drobek-Słowik1, Danuta
Karczewicz1, Krzysztof Safrano2
1Z Kliniki Okulistyki Pomorskiej Akademii Medycznej w
Szczecinie
Kierownik: prof. dr hab. n. med. Danuta Karczewicz
2Z Zakładu Biochemii Katedry Biochemii i Chemii
Medycznej Pomorskiej Akademii Medycznej w Szczecinie
Kierownik: prof. dr hab. Dariusz Chlubek |
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| Summary: |
Purpose: To
evaluate the relationship between cataract, past
cataract surgery and age-related macular degeneration (AMD).
Material and methods: 281 eyes with AMD diagnosed
with fundus fluorescein angiography were included to the
study and divided into two groups: with dry (208) and
exudative (73) type of AMD. 149 eyes without AMD were
controls. We performed ophthalmological examination and
questionnaire. We collected data regarding past cataract
surgery, exposition to the sun, using of sunglasses and
other.
Results: Eyes with AMD were more likely to have
cataract and nuclear sclerosis than controls. History of
cataract surgery was significantly more frequent in
group with exudative AMD compared to controls. Cataract
(OR = 1.93), nuclear sclerosis (OR = 3.84) and past
cataract surgery (OR = 2.32) were associated with
increased risk of age-related macular degeneration in
multivariate analyses adjusted for age.
Conclusions: The concomitance of cataract (especially
nuclear sclerosis) and age-related
macular degeneration may support the theory of common
pathogenesis of both pathologies. There is increased
risk of exudative type of AMD in eyes after cataract
surgery. |
| Słowa kluczowe: |
czynniki ryzyka, zaćma,
zwyrodnienie plamki związane z wiekiem, AMD. |
| Key words: |
risk factors, cataract,
age-related macular degeneration, AMD. |
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