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NR 7-9/2008
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Ocena przydatności
badania mfVEP w diagnostyce guzów przysadki mózgowej
Value of mfVEP test in
pituitary tumors diagnosis
Anna Piekarska1, Wojciech
Lubiński1, Wojciech Gosławski1, Wiesława
Wieliczko2, Anhelli Syrenicz3, Tomasz
Olszowski4, Danuta Karczewicz1
1 Z Katedry i Kliniki Okulistyki Pomorskiej Akademii
Medycznej w Szczecinie
Kierownik: prof. dr hab. n. med. Danuta Karczewicz
2 Z Wojewódzkiej Poradni Endokrynologicznej w
Szczecinie
Kierownik: dr n. med. Wiesława Wieliczko
3 Z Kliniki Endokrynologii, Nadciśnienia Tętniczego i
Chorób Przemiany Materii Pomorskiej Akademii Medycznej w
Szczecinie
Kierownik: prof. dr hab. n. med. Krystyna Pilarska
4 Z Zakładu Higieny i Epidemiologii Pomorskiej
Akademii Medycznej w Szczecinie
Kierownik: dr hab. n. med. Alicja Walczak |
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| Summary: |
Purpose: To
evaluate the mfVEP test in detection of the optic nerve
neuropathy in pituitary tumors.
Material and methods: We examined 30 eyes of 15
patients with confirmed by MRI pituitary tumors (7
patients with macroadenomas and 8 patients with
microadenomas). In all patients the routine
ophthalmologic examination, multifocal visual evoked
potentials (mfVEP) and standard static perimetry
(central 24-2 threshold), were performed. The control
group consisted of 30 eyes of 15 healthy persons.
Results: In 53% (16/30) of eyes manifested
changes in static perimetry and/or in mfVEP test. In 13%
(4/30) of eyes abnormal static perimetry and mfVEP were
simultaneously observed. The only mfVEP abnormalities
were the most frequent feature and were observed in 30%
(9/30) of eyes. Only abnormal static perimetry results
were observed in 10% (3/10) of eyes. In those eyes in
related areas of mfVEP recordings the mean peak-to-peak
amplitude was significantly reduced compare to the
control group. In mfVEP test statistically significant
peak-to-peak amplitude reduction was observed in
superotemporal quadrants in comparison to the control
group (p < 0.009).
Conclusions: MfVEP can be useful test in the
optic nerve dysfunction/ neuropathy diagnosis in
patients with pituitary tumors. |
| Słowa kluczowe: |
guzy przysadki, mfVEP,
perymetria statyczna. |
| Key words: |
pituitary tumors, mfVEP,
static perimetry. |
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