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NR 7-9/2008
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Profil wybranych
cytokin w zapaleniach błony naczyniowej różnego typu
Profile of selected
cytokines in various forms of uveitis
Jolanta Rusiecka-Ziółkowska1,
Anna Turno-Kręcicka2, Anna Białek-Szymańska2,
Ewa Salomon3
1 Z Katedry i Zakładu Mikrobiologii Akademii
Medycznej we Wrocławiu
Kierownik: dr hab. Grażyna Gościniak
2 Z Katedry i Kliniki Okulistyki Akademii Medycznej
we Wrocławiu
Kierownik: dr hab. n. med. Marta Misiuk-Hojło
3 Z Katedry i Zakładu Fizjologii Akademii Medycznej
we Wrocławiu
Kierownik: prof. dr hab. n. med. Ludmiła Borodulin-Nadzieja |
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| Summary: |
Purpose: The
estimation of the level of selected inflammatory
mediators in serum of patients with various types of
uveitis.
Material and methods: The level of IL-1, IL-6 and
TNF was assessed by means of microbiological tests and
ELISA test in the group of 60 patients with uveitis,
divided as regards to the character of uveitis and the
type of the treatment and in control group.
Results: The levels of IL-1, IL-6 and TNF were
higher in serum of patients with uveitis then in the
control group. Patients with known etiology of uveitis
had higher level of IL-6 and TNF. Patients with
autoimmunological etiology of uveitis had higher level
of IL-1 and IL-6 than volunteers in control group.
Conclusions: Higher levels of cytokines in serum
of patients with uveitis than in control group indicate
the activation of immunological response in various
types of uveitis. |
| Słowa kluczowe: |
zapalenie błony
naczyniowej, mediatory zapalenia, cytokiny. |
| Key words: |
uveitis, inflammatory,
mediators, cytokines. |
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