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NR 7-9/2008
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Skuteczność
trabekuloplastyki pneumatycznej (PNT) u chorych z jaskrą
otwartego kąta i nadciśnieniem ocznym – doniesienie wstępne
Efficacy of pneumatic
trabeculoplasty (PNT) in patients with open angle glaucoma and
ocular hypertension – a preliminary report
Joanna Wierzbowska, Andrzej Stankiewicz,
Łucja Romańska
Z Kliniki Okulistycznej Wojskowego Instytutu Medycznego w
Warszawie
Kierownik: prof. dr hab. n. med. Andrzej Stankiewicz |
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| Summary: |
Purpose: To
evaluate the efficacy of PNT in lowering intraocular
pressure (IOP) in patients treated for open angle
glaucoma (OAG) and ocular hypertension (OH).
Material and methods: The study group consisted
of 24 eyes of 14 patients (10 F and 4 M), aged from 35
to 72 (mean 53.7 ± 8.7) who were treated for OAG or OH.
Twelve patients were treated with prostaglandin
analogues (PA) in monotherapy, one patient with PG and
nonselective beta-bloker (BB) and one patient with PG,
BB and topical carbonic anhydrase inhibitor (CAI). The
baseline mean IOP measured with Goldmann tonometry one
hour before first PNT procedure was 20.7 ± 3.3 mmHg (range
16-27). The PNT was performed routinely at 0 and 7-10
day using PNT Unit 1000-Coronado (Ophthalmic
International, Inc., Fountain Hills, Arizona, USA). Then
the IOP was measured monthly and if increased to the
preoperative values the procedure was repeated. The mean
observation time was 6 months, with the shortest and
longest follow-up being 4 and 12 months, respectively.
The IOP changes were estimated one hour after the first
PNT on day 0, then on day 7-10, after 1, 2, 3, 4, 5 and
6 months. A paired Student`s t test was used for
statistical analysis.
Results: The mean IOP measured one hour after PNT
was 19.26 ± 4.0 mmHg (p = 0.17). After 7 days mean IOP
was 17.35 ± 2.64 mmHg (p<0.01), after one month 16.52 ±
2.81 mmHg (p<0.01) and after next months 16.37 ± 2.61
mmHg (p<0.01), 17.63 ± 2.28 mmHg (p<0.01), 15.64 ± 2.06
mmHg (p<0.01), 16.14 ± 3.42 mmHg (p< 0.01) i 16.64 ±
3.14 mmHg (p<0.01), respectively. The mean IOP reduction
was 1.48 mmHg (7.14%) one hour after PNT procedure, 3.39
mmHg (16.35%) after 7-10 days, 4,22 mmHg (20.35%) after
one month, then respectively 4.37 mmHg (21.07%), 3.11
mmHg (15.02%), 5.10 mmHg (24.59%), 4.60 mmHg (22.18%) i
4.10 mmHg (19.77%) after 2, 3, 4, 5 i 6 months of
observation. In 8 eyes the procedure was repeated again
after 3 months, in 4 eyes after 6 months and in 2 eyes
after 12 months. After the procedures transient moderate
conjunctival hyperemia was observed in 24 eyes (100%)
and mild subconjunctival hemorrhagies in 4 eyes (16%).
Lasting a few hours after the PNT procedure foreign body
sensations occured in 3/14 patients (21%).
Conclusions: PNT is an effective method of
lowering IOP in patients treated for OAG and OH. |
| Słowa kluczowe: |
trabekuloplastyka
pneumatyczna, jaskra otwartego kąta, nadciśnienie oczne,
ciśnienie wewnątrzgałkowe, utkanie beleczkowe. |
| Key words: |
pneumatic trabeculoplasty,
open angle glaucoma, ocular hypertension, intraocular
pressure, trabecular meshwork. |
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