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NR 7-9/2009
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Zastosowanie
optycznej koherentnej tomografii w monitorowaniu leczenia
zwyrodnienia plamki związanego z wiekiem metodą terapii
fotodynamicznej
Application of Optical
Coherent Tomography in monitoring age-related macular
degeneration after photodynamic therapy
Jarosław Piłat1, Edward Wylęgała1,2
1 Z Oddziału Okulistyki Okręgowego Szpitala
Kolejowego
Z Samodzielnego Publicznego Zakładu Opieki Zdrowotnej w
Katowicach
Ordynator: prof. dr hab. n. med. Edward Wylęgała
2 Z Zakładu Pielęgniarstwa i Społecznych Problemów
Medycznych Śląskiego Uniwersytetu Medycznego w Katowicach
Kierownik: prof. dr hab. n. med. Edward Wylęgała |
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| Summary: |
Purpose: Of our study is
to check usefulness of OCT exam in qualification for PDT,
and as independent diagnostic tool. OCT exam gives
quantification of parameters for monitoring PDT.
Correlation between the results of OCT exams and visual
acuity was estimated as well as the prognosis of PDT
efficacy on the basis of results from OCT exams
Material and methods: 59 eyes of 56 patients with CNV
caused by AMD were examined and treated PDT. OCT and
BCVA examination were done before PDT, 1 week, 4 weeks
and 12 weeks after PDT. OCT measurement: minimal retinal
thickness in fovea, average retinal thickness in fovea,
retinal volume in fovea and total retinal volume in
macula. STRATUS OCT 3000 with soft. v.4.0.2 (0056) was
used. All 59 eyes form group D. The eyes were divided
into two antagonist subgroup: D1 – 38 eyes with visual
acuity stabilization or worsening and D2 – 21 eyes with
visual acuity improvement 12 weeks after PDT.
Results: There was correlation between results in exams
of retinal thickness and volume in macula. Group D has
significant decrease of minimal retinal thickness,
average retinal thickness in fovea and retinal volume in
fovea 4 weeks after PDT. In subgroup D1 there was
statistically significant decrease of minimal retinal
thickness and total retinal volume in macula, 12 weeks
after PDT. There was in subgroup D1 positive correlation
between relative changes of total retinal volume in
macula and relative changes of BCVA four weeks after PDT.
Conclusions: OCT exam is very useful in qualification
for PDT, but it could not be an independent diagnostic
tool. Useful quantification of parameters in OCT exam
are retinal thickness and retinal volume. OCT does not
allow to prognosis efficacy of PDT. |
| Słowa kluczowe: |
Optyczna koherentna
tomografia, grubość siatkówki, objętość siatkówki,
terapia fotodynamiczna, centralna neowaskularyzacja,
zwyrodnienie plamki związane z wiekiem. |
| Key words: |
OCT, retinal thickness,
retinal volume, PDT, CNV, AMD. |
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