NR. 4/2008



Nowe podejście do leczenia uszkodzeń wynikających z hiperosmolarności łez w zespole suchego oka – osmoprotekcja

Osmoprotection – a New Approach to Dry Eye Syndromes Caused by Tear Film Hyperosmolarity

Pasquale Aragona

Dipartimento delle Specialità Chirurgiche,
Sezione di Oftalmologia, Università di Messina

Summary: Dry eye syndrome is one of the most common disorders encountered in daily ophthalmological practice. A tear film is responsible for optimal conditions of ocular surface in physiological conditions. Despite the type of pathology which leades to dry eye syndromes, developing hyperosmolarity of the tear film is one of the key pathogenetic factors in the development of microinjuries of ocular surface and dry eye syndrome. Osmoprotective agents act through compatible solutes to prevent a hyperosmolar tear film from damaging the ocular surface and it shows very interesting perspectives for treating dry eye syndromes.
 
Key words:   dry eye, tear film hyperosmolarity, osmoprotection.




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